FAUCI DIARY ARCHIVE — Friday, August 5, 2022
https://faucisdiary.com/diary/2022-08-05

Text below is verbatim from the released PDFs, with the original line breaks.
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DIARY ENTRY — Friday, August 5, 2022
Source: Tony's Diary Package, pp. 1016–1018 of 2026.07.24_Tonys-Diary-Package.pdf
Words: 443
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Met with Hans Kluge – WHO Regional Director for Europe. He is seeking my advice on
multiple issues such as COVID, MPX, and vaccine related polio. He said the Europeans
rely very heavily on my opinion:

Heard from Rochelle last night. Latest decision is that they wil hold off on the above
announcement. Had meeting with Bruce Tromberg, Rochelle, Robbie Goldstein and CDC
folks together with FDA folks (Rob Califf and team) and Steve Sha to try to get an
agreement about guidelines for testing for isolation/quarantine when to stop
isolation/masking, etc. We are coming to an agreement that is not perfect, but that is
workable. Had another Zoom with the same team + Dawn O’Connell to explain to her our

POTUS still positive on day 7 following rebound.

****Had a really major victory today resulting from a great collaboration between FDA,
CDC, BARDA, me and John Beigel who was responsible for the design of a trial that would
confirm that the study published in the journal Vaccine in 2015 by Frey et al and Bob
Belshe showed that 1/5 the dose of the MVA monkey pox vaccine administered
intradermally was as effective as a full dose of the subcutaneous administration. When we

made this known to Bavarian Nordic (BN), lower level marketing people in the company
objected strenuously, very likely because they saw this as a diminution in the need for full
doses. Amazingly, they distorted the data and tried to marshal congressional support for
blocking the use of the doses in the 1/5 dilution intradermally. This was an egregious
attempt to interfere with the sound public health maneuver. To make a long story short
when John Beigel showed all the data from the 2015 paper come it became clear that this
was a very important way to expand the number of doses that were available. We finally
got the leadership of BN to agree to continue to ship us the doses since their lower level
people as indicated above were trying to block shipment in order to prevent us from
distributing the vaccine in the 1/5 dilution. After much discussion with the FDA, we finally
convinced them to issue an emergency use authorization (EUA) for the administration of
the MVA vaccine in the1/5 intraderma; dilution. This is a major victory for the prevention
of monkey pox because it turns 300,000 doses into 1.5 million doses and 1,000,000 doses
into 5,000,000 doses. I consider this one of the major victories that I was a part of in trying
to expedite the response to monkey pox.

PRESS: WTOP Podcast with Luke Garrett & Megan Cloherty; CNN with Erica Hill;
MSNBC with Andrea Mitchell;