Monday, June 20, 2022

Tested negative today and have had an essentially asymptomatic course. Began reading Deb Birx’s book “Silent Invasion” and it is clear already from the first couple of chapters that she is revising history regarding her initial involvement. I am sure that part of it is true but it wants me to be careful that I have to be strict to the truth of exactly what happened and not pad it in my favor Important discussions today by phone with me and separately David Kessler, Larry Horowitz, Richard Koup and Peter Marks regarding what the ultimate choice for the booster vaccine for the upcoming fall surge. I have been very concerned of late that we are not carefully analyzing the immunological basis for the choice of a booster shot to be administered before the potentially upcoming Fall surge. The companies Pfizer and Moderna apparently want to give a bivalent of wildtype plus omicron since that is what they already seem committed to and are making. It is my opinion that by the time we get to the fall season omicron will be completely gone and off the map since it is already gone. The closest thing that we likely would see would be a surge of BA4/5. Yet everything seems to be pointing to the decision of doing an omicron/wildtype bivalent. Peter Marks who will make the ultimate decision at the FDA agrees with me that we will be fighting yesterday's war if we go with omicron. There will be many discussions this week that I will catalyze to make sure that we get all the appropriate information for the FDA to make a good decision about the booster.