FAUCI DIARY ARCHIVE — Tuesday, March 2, 2021 https://faucisdiary.com/diary/2021-03-02 Text below is verbatim from the released PDFs, with the original line breaks. ============================================================================== DIARY ENTRY — Tuesday, March 2, 2021 Source: Tony's Diary Package, pp. 637–639 of 2026.07.24_Tonys-Diary-Package.pdf Words: 201 ------------------------------------------------------------------------------ Global – 114,100,000/2,500,000; USA – 28,500,000/513,100 Still coming down, but the slope is changing: Participated in the University of Edinburgh “Futures Conversations” Chaired by Professor Peter Mathieson (Vice-Chancellor, University of Edinburgh) and involving a conversation between me and Professor Nanshan Zhong (China) and Sheila Tlou (former Minister of Health of Botswana) on the global impact of COVID-19. We spoke about global solidarity for vaccine equity. Also, spoke about the variants. Also, spoke about the approach that China took with the outbreak, i.e. complete lockdown Call from Larry Horowitz. Nancy Pelosi is angry about the fact that J & J is being equated with the mRNA vaccines since she has seen the data about the people >60 yo with co-morbidities. Also, she does not like the 72% versus 94-95% for mRNA. She is taking her annoyance out on the medical team (she has not PRESS: Podcast with Kai Kuperschmdt (follow-up from yesterday0; Seattle Gay News interview; Interview for Pritzer Forum/Chicago Council; Hispanicize PSA taping (Paola Ramos); Telemundo 52 Los Angeles; In Washington Post (see below) Fauci: U.S. must stick with two-shot strategy for Pfizer-BioNTech, Moderna vaccines Delaying a second dose to inoculate more Americans creates risks, infectious-disease expert says By Dan Diamond EMAIL — RE: - From: Emily Erbelding To: Karin Bok Sent: Tue, 02 Mar 2021 09:32:38 -0500 Source: Awards & Nominations, pp. 58–59 of 7.24.2026_Fauci-Awards_FINAL_REDACTED.pdf ------------------------------------------------------------------------------ Thanks Karin. I don’t know what Drew Weismann is trying to accomplish with this. Ultimately this is an FDA decision. From: Bok, Karin (NIH/VRC) [E] < @nih.gov> Sent: Tuesday, March 2, 2021 8:51 AM To: Erbelding, Emily (NIH/NIAID) [E] < @nih.gov> Subject: FW: - I am sure you are also dealing with this, my answer to John below if helpful. Karin John, Thank you for sharing. I have no comments or concerns about this study, this is typically what you would see in mice with other types of vaccines as well, and it makes sense that mRNA is present in other sites as well, including placenta, etc. As a side note, I was part of the deliberation with CDC (ACIP/ACOG) that led to the permissive recommendation in pregnancy, and the assumptions from the authors below are very incorrect: Assumption that all of mRNA-LNP degraded at injection site Balancing perhaps differential risk/benefit ratio for maternal health vs fetal health The SMEs on that call (especially obgyns) were aware that mRNA might reach the fetus. The only discussion was around the possibility of that mRNA to integrate into the nuclear DNA. And the second main concern was the fever caused by the vaccine, especially during the first trimester, but they went around that by recommending the administration of acetaminophen after vaccination. Needless to say both mom and baby’s health are important. CDC recently provided a nice overview of the over 30,000 pregnant women who have been vaccinated so far, with more than 200 deliveries with no safety concerns. All vaccines administered to pregnant women historically have been found safe for mother and baby, so when we recently discussed pregnancy and the J&J vaccine, there was no concern, they recommended its use also unanimously. Let me know if you would like us (Emily, myself) to get a second opinion from the obgyns in the special populations working group (mainly Rich Beigi and Flor Muñoz) Thanks! Karin. Karin Bok, MS, PhD Senior Advisor, Vaccine Development Office of the Director, Vaccine Research Center National Institute of Allergy and Infectious Diseases National Institutes of Health phone: | mobile: Released | email: by Chairman @nih.gov Rand Paul https://www.niaid.nih.gov/about/vrc