FAUCI DIARY ARCHIVE — Tuesday, July 7, 2015
https://faucisdiary.com/diary/2015-07-07

Text below is verbatim from the released PDFs, with the original line breaks.
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DIARY ENTRY — Tuesday, July 7, 2015
Source: Diary Prequel, p. 463 of 2026.07.27_Diary-Prequel-.pdf
Words: 208
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Met with team from Gilead Sciences who presented data on their new
compound GS 5734 that has impressive preclinicakl activity against Ebola. They want
our help in testing it in West Africa. It is an RNA Polymerase with activity against
MERS, and likely RSV, Chik, and others. We will help them and do a trial in West
Africa after we finish the ZMapp trial that is moving along well (47 subjects thus far) in
Sierra Leone and soon in Guinea. Infections persist in both countries. Also, last week
there was an infection in Liberia with 2 secondary cases.
The Gilead people were: Andrew Chang (Head of HIV Therapeutics & Development
Operations; William Lee (Head of research); Howard Jaffe (Senior Advisor); and Tomas
Cihlar (Head of Discovery Virology).

Also, Cliff is back from Guinea and it looks like (despite the continued objections of tom
Frieden), we will expand the RCT Vaccine trial into Guinea where there are persistent
cases.

Had diner tonight at Grapeseed restaurant in Bethesda with the BMGF people who are in
town for our yearly joint gates/NIH meeting. Francis Collins and I and Doug owy were
the senior NIH people there and Trevor Mundel, Emilio Emini, Chris Carp, Chris Wilson
were senior Gates people among others.