FAUCI DIARY ARCHIVE — Wednesday, July 9, 2014
https://faucisdiary.com/diary/2014-07-09

Text below is verbatim from the released PDFs, with the original line breaks.
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DIARY ENTRY — Wednesday, July 9, 2014
Source: Diary Prequel, p. 346 of 2026.07.27_Diary-Prequel-.pdf
Words: 181
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PCR confirms that the Mississippi Baby has indeed rebounded with virus
at 16,000 and 10,000 copies RNA per ml. Baby has been off cART for 27 months and is
46 months of age. Disappointing, but raises many questions. The baby had no
detectable immune response for these many months. Since the virus was obviously there
in a reservoir somewhere, what then was the mechanisms that was preventing it from
rebounding. Will hold press conference with Deb Persaud, Hannah Gay, and Katherine
Luzuriaga on Thursday (tomorrow).

Had interesting rounds today to see our first patient (Phil Diers) that received an
allogeneic PBMC transfer from a HLA-B27 HIV-infected Elite Controller donor.
Recipient has CD4+ T cell count of 0-4 and >150,000 copies of HIV on cART (resistant
virus). Hope is that the immune response of donor cells will impact in some way the
infected cells of the recipient. More to come. Way out chance of a graft versus infected
cell effect that might eliminate reservoir (too much to ask for). See picture below of me
on Rounds the day after the allogeneic transfer.